C-Focus System
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Questions?
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Features
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Typical Applications
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Product Description |
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C-Focus systems provide an automatic means to eliminate
microscope focus drift over long time periods.
Unlike autofocus systems which require use of advanced
microscopes with internal focus correction or external
devices which track video signals or reflected laser beams,
the C-Focus simply corrects for microscope focus drift by
using a high resolution (5nm) sensor system to measure
the lens/sample spacing and make the necessary adjustments.
The C-Focus system has no effect on standard
manual focusing and can be retrofit to any microscope.
After focus is established, simply pushing the “focus lock”
button starts the C-Focus operation. Objective lens motions
are accomplished with a lens nanopositioner (the Nano-F100S) which is easily connected to the objective
lens and microscope with standard threaded adapters.
In addition to the unique C-Focus operation, lens nanopositioner
motion can also be directly commanded by
digital (16-bit USB) or analog signals and can be used
for high speed, high resolution confocal imaging and
other imaging tasks with demanding focus requirements.
The C-Focus lens positioning system contains the same
proprietary, low noise PicoQ™ position sensors used in
the Nano-F100S and is capable of sub-nanometer positioning
resolution. The 16-bit USB digital computer
interface is included with all C-Focus controllers. Compatible Software Packages:  |
C-Focus Data |
| Set of Cy3 single molecule imaging Sample: MutS protein imaged with Cy3 in presence of oxygen scavenging system Technique: Prism TIRF Microscope: Olympus IX-71 Objective: 60x 1.45NA Oil Immersion, 1.6x magnification Camera: Hamamatsu EMCCD  Courtsey of: Biomolecular & Cellular Dynamics Lab Dept of Physics/IBIO, POSTECH South Korea http://jblab.postech.ac.kr |
Focus Drift vs. Constant Focus |
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Technical Specifications |
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| Range of motion (Nano-F100) | 100 μm |
| Resolution | 0.2 nm |
| Resonant Frequency | 500 Hz ±20% |
| Stiffness | 1.0 N/μm |
| Recommended max. load* | 0.5 kg |
| Body Material | Al and Brass |
| Controller | C-Focus |
| * Larger load requirements should be discussed with our engineering staff. | |
Additional Information | |
Nano-F100 Drawing |
C-Focus System |
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