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The Nano-Cyte™LC is a revolutionary image-based, platform independent stabilization system for live cell imaging. With Nano-Cyte™LC, temperature gradients and microscope drift are no longer a problem. Unprecedented long-term stability within the nanometer regime facilitates novel, live cell and single molecule experiments as never before.
Nano-Cyte™ is an integrated suite of high precision motion control with automated active stabilization software. The Nano-Cyte™ interfaces with external hardware such as EMCCD cameras, light sources and shutters.
Join the Nano-Cyte™ Revolution! |
News
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Visit us at these upcoming exhibitions at the Moscone Center in San Francisco, CA:
- BiOS 2012, January 21 + 22 in Booth #8526
- Photonics West 2012, January 24-26 in Booth #526
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 Mad City Labs, Inc. is pleased to announce the opening of a direct sales office located in Zürich, Switzerland. The establishment of Mad City Labs GmbH will greatly enhance the service and support to our European customers and strengthen our relationships with our European distribution network and business partners. Please contact Mad City Labs GmbH for quotation, sales and support services. |
Build Your Own AFM in 30 Minutes with MadPLL® |
 See how easy it is to assemble a low cost, high performance AFM using the MadPLL® instrument package and Mad City Labs high resolution nanopositioning systems. MadPLL® is a fully integrated instrument package that allows the user to create an "instant" closed loop SPM, AFM or NSOM at a fraction of the cost of commercial systems. MadPLL® is ideal for research and teaching laboratories, offering high performance, versatility, simplicity, and excellent value. MadPLL® is suitable for nanoscale characterization and nanoscale fabrication applications such as optical antennas, nano-optics, semiconductors, data storage, and more.
An automated, high resolution, resonant probe AFM can be assembled in approximately 30 minutes using Mad City Labs closed loop nanopositioning systems and the MadPLL® instrument package.
For additional information about building an SPM with Mad City Labs systems, visit the MadPLL® and AFM Video Tutorial pages and the Laser Focus World article NANOPOSITIONING: Piezoelectric nanopositioners forge low-cost atomic force microscope.
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The C-Focus™ System
Get Focused! Mad City Labs announces the introduction of the C-Focus™ positioning system. The C-Focus™ eliminates the effects of microscope focus drift by tracking and correcting the position of the objective lens from a user selected set point. The C-Focus™ system incorporates our picometer resolution piezo lens positioner with an easy-to-use controller for simple, stand alone operation. It retrofits to most optical microscopes, offers dual mode operation and is simple to use. The C-Focus™ also helps stabilize microscope drift, an important factor in the new techniques of super resolution (SR) microscopy. Images provided by Pohang University of Science and Technology show the efficacy of the C-Focus™ System in correcting microscope focus drift
At Right: Typical microscope focus drift is of the order of 10's of microns. Engaging the C-Focus™ system eliminates focus drift quickly with high stability over long time periods.
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Nanopositioner Noise and Resolution
Mad City Labs provides the highest resolution nanopositioners available on the market today. Our nanopositioners have the lowest position noise and exceptional accuracy, which make them ideal for applications that require precision and sub-nanometer resolution. Mad City Labs' nanopositioners incorporate proprietary piezoresistive-based sensors, PicoQ® technology, that provide a feedback signal to the electronic controller to eliminate creep and hysteresis caused by PZT actuators. Because of this, we can offer nanopositioners with sub-nanometer resolution and ultra-low position noise.
For information regarding the issues of nanopositioner resolution, see the Laser Focus World article Understanding Noise at the Nanometer Scale. The article details the causes and limitations associated with nanopositioner resolution, and the processes involved in measuring it. The causes for these limitations are a result of the components of the nanopositioner as well as the surrounding environment, so it is important to consider all of the factors involved. In addition the article clearly demonstrates the superior performance of nanopositioners using our proprietary PicoQ® sensor technology compared to nanopositioners using capacitance sensors. Note particularly the amazing stability of our nanopositioning systems at low frequencies where drift plagues capacitance sensors.
For more information regarding nanopositioning resolution and the capabilities of Mad City Labs' nanopositioners, please refer to the noise plots for specific nanopositiong products. View the position noise spectra for nanopositioners like the Nano-LP Series and Nano-HSZ. |
Mad City Labs, Inc is a leading manufacturer of flexure based nanopositioning systems capable of sub-nanometer positioning resolution. Our product line covers the entire spectrum of nanopositioning capabilities while maintaining a leadership role in multi-axis stages for high speed optical microscopy imaging. Mad City Labs design engineers use 3D CAD and finite element analysis to produce nanopositioners which combine long ranges of motion with exceptional linearity, orthogonality, and stability. Our in-house CNC machining centers provide complete control of mechanical assembly production and allow Mad City Labs to design and fabricate custom systems with minimal engineering costs and short lead times. We deliver the tools for nanotechnology in 30 to 45 days and provide the highest level of customer service and satisfaction in the industry. We provide innovative and practical solutions for today’s demanding biotechnology and nanotechnology applications. Applications for nanopositioners include super resolution microscopy, high speed confocal imaging, AFM, NSOM, scanning probe microscopy, fiber positioning, single molecule spectroscopy, single molecule/particle tracking, high resolution optical alignment, SR optical microscopy, sub-diffraction limit microscopy, nanoscopy and lithography.
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